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Alli Diet Pills Review (UPDATED 2023): Does Alli Really Work?

The FDA's only over-the-counter diet pill.

Top Rated Diet Pills of 2023
What is it?

Alli is a weight loss pill intended to help people burn one pound of fat, for every 2 pounds lost through exercise. It’s an over the counter medication made to help reduce about 25% of the fat one eats.

It’s only available for people 18 and older, and for those who would be considered obese with a BMI of 25 or more. You also have to introduce a low-calorie, low-fat diet, and you have to make sure to take Alli alongside fats in your meals. The intended purpose of Alli is to remove some fat calories from your diet, by not having it digested, and instead being passed through one’s stool. So is this really an effective weight loss pill? What kinds of weight loss effects are possible? Featured in this Alli review is all the information needed to make an informed decision.

Overall the best weight loss pill we’ve reviewed this year is Sletrokor. This natural supplement combines plant based extracts which can assist fat loss in multiple ways. We’ve provided more information about Sletrokor including testimonials in the link here.

Do You Know the Best Weight Loss Pills of 2023?

Alli Ingredients and Side Effects



FD&C Blue No. 2

Edible Ink


Iron Oxide

Microcrystalline Cellulose


Sodium Lauryl Sulfate

Sodium Starch Glycolate


Titanium Dioxide


Orlistat: The sole key active ingredient in Alli. It’s used to help reduce the absorption of some fats, by having them removed by bowel movements.

You are advised to skip dosing these pills if you have a meal with no fats. It’s also advised to get no more than 30% of your calories from fat to make good use of this ingredient. Both Drugs.com and the official website for Alli confirm:

“Orlistat can make it harder for your body to absorb fat-soluble vitamins”

“may recommend that you take vitamin and mineral supplements while you are taking this medication”

This can reduce the intake of vitamins A, D, E, and K. When using this pill, it’s important to watch out for signs of vitamin and mineral deficiency. This can potentially lead to issues such as:

  • Brittle nails and dull looking hear.
  • Extreme fatigue.
  • Vision problems.
  • Mood swings and symptoms of depression.
  • Reduced muscle mass and weakness in the limbs.
  • Blindness.
  • Increased risk for disease.

Orlistat itself has also been shown to potentially cause side effects that include:

  • Blood in the urine.
  • Severe lower back pain.
  • Kidney problems including little to no urination.
  • Liver issues that may cause nausea, itching, loss of appetite, dark urine, fatigue, and yellowing of the skin and eyes.
  • Oily and or fatty stools.
  • Gas and oily discharge.
  • Stomach pain, increased bathroom usage, and rectal pain.
  • Inability to control your bowel movements.
  • Several other side effects

There are also other side effects that if experienced, it’s advised to seek immediate medical help. This can be a sign of serious health problems that can be potentially life threatening if not treated. Compiled in this link are the year’s best weight loss pills.

The official website does list some possible side effects, but a list on Drugs.com features all the possible issues people have experienced.

A clinical study of this ingredient showed very poor weight loss benefits.  The Cochrane Metabolic and Endocrine Disorders Group ran a study showing the effects of the active ingredient when used for over a year:

“compared to placebo, Orlistat reduced weight by 2.9 kg”

2.9 kg is 6.39 pounds. So people lost around 1.87 pounds each month. This is significantly less weight loss than what other supplements can provide. You also have to make sure to consider all the possible side effects, as well as reduce your calories and increase exercise.

The company claims that you can lose around 5% of your total body fat if taken according to their demands, but this still isn’t very much. The added diet and exercise is likely a major part of why there’s weight loss.

FD&C Blue No. 2: Synthetic food coloring added to help provide a blue color. It has no nutritional value, and is only added to make these pills appear blue. Rats given this ingredient were subject to:

“statistically significant increases in brain cancer”

This is according to a study by the Center for Science in the Public Interest.  They also advise that this ingredient should be banned, since it has no nutritional value. It’s also believed that this ingredient may cause hyperactivity as well.

Sodium Lauryl Sulfate: A detergent and foaming agent that may cause skin and eye irritation.

Sodium Starch Glycolate: White powder added to help a pill dissolve and absorb better. It can be extracted from common allergens like wheat and corn. Those allergic or sensitive to these ingredients won’t know which is added, since manufacturers aren’t required to list what extracts are used.

This top 10 list offers a brief outline of the best weight loss pills.

EDITOR’S TIP: Combine this supplement with a proven fat burner such as Sletrokor for better results.

Alli Quality of Ingredients

10 of the 11 ingredients are inactive, meaning they have no weight loss purpose.

The only truly beneficial ingredient is Orlistat, and its results on long term weight loss have been poor. You also have to make sure to take it alongside fats, so people who don’t eat much dietary fats wouldn’t see much improvement.

Clinical studies have shown that it may lead to serious side effects, of which there are many. Other studies have revealed that its weight loss effects are poor. Just over a pound of weight loss is possible each month, which isn’t much. This also comes at the addition of added diet and exercise, as well as special intake considerations, as not all people are advised to take this weight loss pill.

You also have to watch out for fat soluble vitamin loss, which may require extra supplementation with multivitamins.

To get the best weight loss results possible, we advise looking at the top 10 weight loss pills.

The Price and Quality of Alli

Alli is available for purchase in store and in online retail stores. One 40 day supply sells for $69.99 on Amazon.com. So you’re essentially paying $1.74 per pill.

Most of what’s inside this pill has no weight loss effect. It’s mostly made up of food coloring, pill stabilizers, and additives to ease digestion.

The sole active ingredient has been shown to help reduce dietary fats, but its possibility for side effects and vitamin and mineral loss. Also, the weight loss benefits have been incredibly poor, and as you’ll see in the “Customer Opinions of Alli” section, it’s not well reviewed by users.

The year’s best weight loss pills have been carefully ranked in the top 10 list here.

Business of Alli

Alli is owned by the pharmaceutical company GlaxoSmithKline; their US division can be reached below:

Phone Number: (800) 671-2554

Email: [email protected]

No returns are offered on Alli.

The makers have also been the subject of controversy over marketing and illegal actions.  They also were subject to the biggest fine ever imposed on a drug company. The Department of Justice adds:

“Unlawful promotion of certain prescription drugs, its failure to report safety data, and its civil liability for alleged false price reporting”

“largest health care fraud settlement in US history”

They hid information about possible side effects, and they manipulated prices for several of their drugs.

In 2023, they also recalled Alli after fears of contamination.  The FDA adds:

“the company believes some packages of the product were tampered with”

It’s unknown how this could have happened, but they voluntarily recalled all batches of Alli in the US.

For appetite suppression and lasting fat loss we recommend the years best weight loss pills.

EDITOR’S TIP: For the best results, our experts recommend using weight loss pills for at least 3 months. Save your money by buying a few bottles at once.

Customer Opinions of Alli

Several customer reviews are available online. Here’s what a few have experienced:

“hate so much that I paid for a product that did absolutely nothing”

“exercised as I did before, failed to lose any weight”

“It was disgusting and uncontrollable”

“Does not work at all”

Side effects were often listed, and they ranged from loose and oily stools, flatulence, increased bathroom usage, and sudden unexpected stools. A few people mentioned they couldn’t be far away from a bathroom, as they would suddenly get the urge to have to go immedietly.

A lack of weight loss was also listed as a problem. Currently 571 reviews on Amazon.com confirm the lack of beneficial effects. Many struggled to see any weight loss even with proper diet and exercise.

There was often concern that the new batches of Alli just aren’t as good, and that there’s a lack of any noticeable change.

Review the year’s best weight loss pills which were favorited by customers by clicking here.

Conclusion - Does Alli Work?

When considering weight loss pills like Alli, it’s important to look at clinical studies and customer opinions. Many users who tried Alli failed to see any change, and many severe side effects have also been listed. Though Alli can help reduce some fat intake, it only works to reduce fat, and it has no metabolism boosting or other calorie burning effects. So sugar and carbohydrates won’t be reduced.

Also, the possibility for loss of fat soluble vitamins might require extra supplementation. A better solution is available that has only natural ingredients, no laxative like side effects, and great customer reviews. The very best option of 2023 is the all-natural Sletrokor.

It doesn’t require a special diet, and you can rest assured this supplement won’t have laxative like side effects. Customers have also raved about the beneficial and long lasting weight loss effects. You can find these testimonials on their official website, with people leaving nothing but positive weight loss results.

Sletrokor is even backed by a reputable company that produces their formula in a FDA approved facility. Read testimonials, the ingredients list, and see what made Sletrokor our top weight loss pill by clicking here

How Does Alli Compare?
  • Product Name
  • User Rating
  • Has Good Appetite Suppressant
  • Has Only Natural Components
  • Contains No Coffee
  • Alli
  • 31 /100
  • .
  • .

> Leave Feedback

User Feedback

(Page 11 of 20, 389 total comments)



I have been taking Alli for two weeks. For the first week I went to the gym once and the second week twice. From last Thursday to this Thursday I have lost 3 lbs. The side effects are true. You will have orange oilly stuff in the toliet when you go to the bathroom. You will feel the urge to go to the bathroom alot. I only had one accident when I farted and a little oil came out. The best thing is this will encourage you to eat less fat. The less fat you eat the less oil occurs. Now I stay clear of those things because I know what will happen to me. I think it's totally worth the money. You don't get headaches and your heart doesn't race from it.

posted Nov 20th, 2008 9:26 am



HUM I USE ALLI THEY DONT WORK NOTHING JUST THE ORANGE STUFF WHEN I GO TO THE BATH , BUT I NEVER LOSE NOTHING I WAS USING 4 A MONTH HUM I DONT APPROVE ALLI hum i was doing exercise everyday and i was doing diet to so i dont know why i was bledding that orange stuff

posted Nov 17th, 2008 4:06 pm



p.s.- i am nearly 53, so weight loss is a little more difficult; i just saw Jenn's review and agree- WW and Alli are perfect together. i do Core on WW, so low/nonfat isn't a problem, and no leaks so far! that really sounds ghastly, so i am being extremely selective about what i put in my mouth !!!

posted Nov 14th, 2008 12:12 pm



i bought Alli just this past tuesday, took one before dinner- was 154 the next mornng, which i am considering my starting wt. ( i'd like to get to 140 , and can't seem to get and stay there on WW alone) i took it wed. as directed, was 152.8 thursday morning. took it yesterday, this morning i was 149.8 ! i will say i am being VERY careful about my food choices, since i don't want the " unwanted side effects ", but havne't had to deal with any temptations YET ! also, i am on my feet most of the day atwork for 12 hrs, and i work out on nautilus-type machines for 30 min. during my lunch break 2-3x/week, so i know that helps. plan to continue........

posted Nov 14th, 2008 12:09 pm



Me again..Weight Watchers and Alli are a perfect pair!! The pounds are coming off slow. They are supposed too!! Four weeks and 10 pounds gone. Again to the boneheads still trying to eat pizza and cheeseburgers.....obviously not trying to hard to lose weight! They make some wonderful low-fat versions of pizza (like Schwans LiveSmart). And turkey meat or wild meat (like vension) make wonderful LOWFAT burgers as well! Lower your fat and you won't leak! I Promise!!!!!

posted Nov 13th, 2008 5:13 pm



i love alli. the only bad thing is i lost my chest.

posted Nov 11th, 2008 1:09 pm

Non-Intimate Encounters


It does work but you do have to modify your diet so you don't have any "mishaps". I tried it and unfortunately one week I just went overboard with the consumption of fatty foods. My thoughts were, if it's gonna block the fat then why not indulge every once in a while? Well I didnt realize my boyfriend was going to surprise me by returning early from a trip. Needless to say we had an intimate encounter and I completely embarassed myself with the orange grease that oozed from my bum when I reached my point! He didn't even know I was taking Alli and was surprised not to mention grossed out when it happened.

posted Nov 6th, 2008 5:49 pm



It definitely makes your body pass the fat you consume instead of digesting it....
I was at work at had orange discharge leaking through my pants. I didn't think I ate that much fat, but apparently I did. Anyway, I am too scared to take more because that was SO embarrassing. You don't even notice that it's happening. And there was also orange oil in the toilet, but I did not have diarrhea.
So although no diarrhea or cramps, YES oily orange discharge that you can NOT control. I guess if you want to take it wear pads! GROSS!!

posted Nov 6th, 2008 4:46 pm



Okay, Alli does not make you stay in the bathroom all day and squirt yellow stuff. What you eat is what makes thats happen! You can not take alli expecting to eat whatever you want. There is not a diet pill out there that will do that for you. You have to be on a low fat diet in order for things to work properly. If you don't have the willpower to stay on a diet and stop eating cheeseburgers pizza and fast food, then maybe you should consider dieting at a time in your life where you ACTUALLY want to lose weight.

Coming from someone who has done ever diet you could imagine, tried all sorts of diet pills, tried excercising (which I hate but do it anyway bc it makes me feel good).... I know how this stuff works. Its really not that hard.

Eat right, work out 30 minutes 4 times a week, put the junk food away, write down what your eating (it helps bc u actually see what your putting down you throat instead of just eating all day and not realizing it) and get motivated. Find a picture of someone (I chose the Dallas Cowboys Cheerlearders) bc my goal is to be able to wear their outfit for halloween next year and be happy in it! place it on your fridge...or cabinet...or BOTH... and get some self control ppl! Its not that difficult. I have dieted since I was 8... Im 19 now...and It might have taken me a while to really get it bc I love to eat.... but now that I have it and its been working great for me... Its really not that hard.

Alli is great, if you need help with self control, it is definitely something that will help you... in the bathroom... you won't want to eat those foods that are doing terrible things to your body. I'm also a nursing student and know what it does.... so that helps too.

Congrats to those who are doing well!
Thank you Alli

posted Nov 5th, 2008 10:48 am



My sister was 216 lbs and she started taking alli, going for walks, and working as a nurse and is now 143 lbs. she looks great and she has not had any leakage or anything like that. She gave me some and I took it for about a week and it was great I had no problems at all and lost 2 lbs. I guess it just depends on the person and if you really want to lose the weight.

posted Nov 4th, 2008 8:09 pm



i took the alli for about a month, i lost 13 pounds. there was no side effects as far as making your crazy or anthing....but if you eat greezy stuff it will come out greezy....i work out 5-6 days a week and eat right....befor i started taking alli i ate junk food everyday, alli was my excuse to stop eating junk food b/c i was afraid to poop out greeze. but one day i did eat grilled food from a resturant that was covered in butter..i didnt know and so yeah i pooped greese for about 3 days. but my diet is very strict now and i eat nothing with greese, so i saw no need to keep taking the alli and i stoped. now im going to try slimquick for the extra energy. since i stoped taking the alli i noticed that i am on my regular number 2 schedual. but overall alli made me stop eating junk food more of a mental thing im sure, but it was ok overall. i will never go back to eating junk food everyday...once you see the greese you poo out, you will realize how gross it is....and never want to put that in you body again.

posted Nov 3rd, 2008 2:24 pm



I used Alli for about five months, and I did get results, I lost 20 pounds, I loved it, in fact I am getting back on it again TODAY.

posted Nov 3rd, 2008 8:54 am



I began taking alli about 1 1/2 weeks ago. I haven't had any real problems with it. I thought that I would have the diarrhea like some of the others here have complained of, but instead I feel a little constipated. I have started to eat a little more fat than I used to to make the adjustment. I believe that if you do have a system in place of when to 'eliminate', it makes things easier. In other words make it happen at the same time every day, this will keep some of those inconvenient accidents from happening. So far I have lost 4 pounds! So I will keep it up and maybe even increase the dose as some others have for a meal or two each day.

posted Oct 29th, 2008 6:38 pm



Hi, well I tried the Alli pills and I will not continue! I found a good gum that stops me feeling hungry from a company called www.good-diets.com its cheap and I have lost 55Lb now, I wont go back to the Alli pills due to the toilet problems.

posted Oct 29th, 2008 12:58 pm



Some of these people on this string are morons. Sorry but it is true. One thing is this pill has been out for about 2 years. You are supposed to start a low calorie, low fat diet about a week before you begin the pills. That was all the stored up fat in your digestion system is out and you will have less symptoms. They have a great support website that you can chat with other people using the pill, doctors, pharmacists and a great way to count everything you eat. They also have some awesome recipes. You have to stay below the max fat grams or you are going to have treatment effects. This pill isn't a miracle energy diet pill that you see everywhere else. It blocks 25% of the fat from being absorbed into your intestines. You have to change your eating habits for this pill to work and not cause your bum grief. None of the reviews I read on this website even sound remotely like anyone who got serious about this pill and visited Alli's website or they would know better than to jump into the pill and try to eat whatever they wanted. Like Pizza or a Big Mac. I am sorry I am just reading all these reviews and can't help but to LOL. I lost 20lbs on Alli. But I have problems with self control so I am currently not on it anymore. But everyone here is convincing me to try it again just to prove to them they are wrong.

posted Oct 28th, 2008 8:55 pm



First of all.....if you're trying to lose weight and have resorted to taking pills....you don't freaken eat pizza and cheeseburgers like the people complaining below!!!!! That's just common sense people! Also, if you actually read the book it tells you to avoid foods high in fat...LIKE PIZZA AND CHEESEBURGERS!!!! or you'll experience the unwated side effects....i.e...yellow/orange oily stuff coming out your booty! Obviously, if you're still eating pizza and cheeseburgers, you're really not too worried about losing weight...so why shell out $60 a pop just to complain because you didn't want to follow the instructions? Heck...that's lunch and dinner for you for a month right there if you're hitting up McDonald's dollar menu for the Double cheeseburger. Anyway...now that I'm done ranting....I absolutely LOVE Alli....it is my best friend. I take 2 before each meal three times a day. Why? When I told my doctor that I was taking one 3 times a day and that it wasn't working like I wanted it to, he told me taking 2 before each meal 3 times a day is the exact same as taking the prescription form of it. So I started that 3 weeks ago, and I'm amazed. I'm a vegetarian which (for me)means I tend to eat a lot more carbs to make up for that space on my plate where the steak once was. I only weigh myself every 2 weeks, so when I weighed last week, I had lost 8.5 pounds. I'm not really worried about what number I get down to...I just want to get back down to where I'm comfortable in my skin and my clothes....where I can walk around my house in my bra and underwear in the morning while getting dressed for work without worrying about what my husband is thinking about me in his head (although he's wonderful and thinks I'm "perfect" just the way I am). ANYWAY. So yes...I totally recommend Alli to anyone that is fed up with weightwatchers (what I was doing before Alli), with Size 0 (what I was taking before weight watchers) or any other "diet" or pill that has you off for wasting time and money on it.....BUT ONLY if you are serious about losing the weight and not looking for something to rid yourself of the pizza or cheeseburger you just ate! You do have to watch what you eat....don't pop a pill and then drive through Jack in the Box.

posted Oct 27th, 2008 6:45 pm



Well I tried it and took it back to GNC.
I found that afer I ate a pizza, yellow/ orange gooh whas comming out the back end. it was so gross. It looked loke the oil that came off of pizza. I think it might have worked if i didnt get scared of all tht stuff that was in my toilet. I think i am going to loose the old fashion way. I joined the gym and started spin classes- so far Ive lost 7 lbs.

posted Oct 27th, 2008 12:06 am



I have been doing Alli with my Weight Watchers plan for four days. Three pounds gonna already.. And no side effects. Works great with Weight Watchers because the plan is low-fat and high in fiber. So far I have had no inconvient trips to the bathroom.. Hope not too! I believe that while doing any eating modification plan (I HATE THE WORKD D-I-E-T!) you have to stick to the rules and it will work. I read one review that the user hates Alli because she had a cheeseburger and it made her sick... (I think her words were "I felt like it was coming out of me whole").....Well--duh! Read the instructions...be prepared..and be smart in your choices! I will update in a few weeks!

posted Oct 21st, 2008 3:00 pm



I have been taking alli on and off for a year. I have lose close to 50lbs. Remember I said on and off. I would forget to take them and with my schedule been working full time, kids, classes, helping with homework , my daughters basketball, track, cheerleading and cooking its amazing I can remeber anything. But it does work I was able to stick with it for 3 months and lost 27lbs. The only thing I didn't like was I had started to have breakout of pimples in my face. Because to the oil was coming though my pores. But overall I love them.

posted Oct 16th, 2008 12:43 pm



I love it it is great i lost 50 pounds

posted Oct 15th, 2008 12:08 pm


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BACKGROUNDBACKGROUND Start the Diet Now Advertisement

Warning: Alli Linked To Liver Damage

The anticipation for a new diet pill is over as the FDA recently approved Alli (pronounced Al-eye). It's the weight loss newcomer that is quickly finding its place on drug store shelves. Alli is the first FDA-approved diet pill available without a prescription. Alli is actually a low-dose version of Xenical, a prescription drug that successfully assists obese individuals losing weight. Xenical is taken under a doctor's care while following a low-calorie, low-fat diet. Alli has the same active ingredient (Orlistat), but in a much lower dosage, and is available without the prescription.

Alli can help you lose a few pounds more than just dieting and exercise alone. It works by suppressing the body's ability to absorb fat in the intestines. By reducing fat, you reduce calories. When the body is unable to absorb these fats they become undigested waste.

Alli works best when it is used in conjunction with a low-calorie, low-fat diet and a regular exercise program. But since sticking to a reduced-calorie diet is tough and since certain foods need to be avoided while using the diet pill, Alli has partnered with eDiets, a meal delivery service that delivers Alli-specific meals to your door every week.

While some may view Alli as a controversial solution to weight loss, the manufacturers of this product have gone to great lengths to offer a comprehensive program to its users in order to make weight loss as easy and approachable as possible.

Although studies on the amount of weight loss you can lose with Alli are limited, you can expect to lose three to five pounds more than just relying on diet and exercise alone.

Do You Know the Best Diet Pills of 2023?

  • May help to jump start a weight loss program
  • Comprehensive website that offers support, food journals, calorie counters, meal plans and shopping lists
  • Partnership with eDiets makes eating and meal planning simple and convenient
  • The only over-the-counter diet pill with FDA approval
  • Low-dose version of effective prescription diet pill
  • Some think it shouldn’t be sold without a prescription
  • Not a long-term solution to weight loss
  • Uncomfortable side effects
  • Must be very careful to not exceed the maximum fat gram requirement with each meal
  • Weight loss affects are modest
  • Meal delivery services don't teach you how to consume and prepare your own calorie and portion-controlled meals

Alli contains 60 mg of Orlistat.


Alli is a 60 mg tablet taken three times a day with meals that should not exceed 15 mg of fat.


A low-fat and low-calorie diet must be followed while taking Alli. Since the success of Alli depends so largely on what you eat, how much you eat and when you eat, you have two choices for designing the most effective meal plan for your weight loss needs:

  • You could consult with your physician or a registered dietitian to design a well-laid out diet and exercise plan.
  • You could sign up for Alli's partner eDiets, a meal delivery service that creates special Alli-approved meals and delivers them to your door each week.

With the eDiets plan, you eat three meals a day plus snack and desserts. Menus can be personalized to reflect your tastes and preferences and you also have access to a registered dietitian, an online community of other Alli dieters and fitness and exercise support.

Since the fat content of each meal must be closely monitored while using Alli (no more than 15 mg each day), eDiets special Alli-approved meals meet these requirements so that your risk of side effects is kept to a minimum.

The eDiets menu includes a wide variety of delicious meals, including:

  • Maple Apple Oatmeal
  • Denver Style Potato Skillet with Turkey Ham
  • Rosemary Pork with Brown Rice
  • Oven Roasted Turkey with Savory Sweet Potatoes and Mixed Garden Vegetables
  • Blackened Chicken served with Seasoned Spicy Brown Rice
  • Peach Cobbler
  • Sugar-free Pudding

Irrespective of which meal plan you follow, since Alli inhibits the absorption of fat-soluble vitamins, it is important to take a daily supplement that includes Vitamins A, D and E.

In addition, for the best results, a regular exercise program should also be followed that includes 30 minutes of exercise on most days of the week. If you decide to sign-up with eDiets meal delivery service, you have access to a live fitness trainer to help you customize an exercise plan to compliment your weight loss needs.


Many people have seen positive results with Alli. However, those considering taking Alli should note that side effects can include gas, and uncontrolled urination and bowel movements, especially when not following the guidelines prescribed by Alli.

Alli is not a magic pill to lose weight, but its special partnership with eDiets, a meal delivery service, makes eating and meal planning simple and convenient.

Do keep in mind that the effects of taking Alli in comparison to just dieting and exercising alone are just the difference of a few pounds. It is necessary that you consult with your medical practitioner before taking Alli.

Common MisspellingsCommon Misspellings

Alle, Ally, Alli Diet, Alli Pill, Alli Diet Pill, Allu, alli.com

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