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Alli Diet Pills Review (UPDATED 2022): Does Alli Really Work?

The FDA's only over-the-counter diet pill.

Top Rated Diet Pills of 2022
What is it?

Alli is a weight loss pill intended to help people burn one pound of fat, for every 2 pounds lost through exercise. It’s an over the counter medication made to help reduce about 25% of the fat one eats.

It’s only available for people 18 and older, and for those who would be considered obese with a BMI of 25 or more. You also have to introduce a low-calorie, low-fat diet, and you have to make sure to take Alli alongside fats in your meals. The intended purpose of Alli is to remove some fat calories from your diet, by not having it digested, and instead being passed through one’s stool. So is this really an effective weight loss pill? What kinds of weight loss effects are possible? Featured in this Alli review is all the information needed to make an informed decision.

Overall the best weight loss pill we’ve reviewed this year is Sletrokor. This natural supplement combines plant based extracts which can assist fat loss in multiple ways. We’ve provided more information about Sletrokor including testimonials in the link here.

Do You Know the Best Weight Loss Pills of 2022?

Alli Ingredients and Side Effects



FD&C Blue No. 2

Edible Ink


Iron Oxide

Microcrystalline Cellulose


Sodium Lauryl Sulfate

Sodium Starch Glycolate


Titanium Dioxide


Orlistat: The sole key active ingredient in Alli. It’s used to help reduce the absorption of some fats, by having them removed by bowel movements.

You are advised to skip dosing these pills if you have a meal with no fats. It’s also advised to get no more than 30% of your calories from fat to make good use of this ingredient. Both Drugs.com and the official website for Alli confirm:

“Orlistat can make it harder for your body to absorb fat-soluble vitamins”

“may recommend that you take vitamin and mineral supplements while you are taking this medication”

This can reduce the intake of vitamins A, D, E, and K. When using this pill, it’s important to watch out for signs of vitamin and mineral deficiency. This can potentially lead to issues such as:

  • Brittle nails and dull looking hear.
  • Extreme fatigue.
  • Vision problems.
  • Mood swings and symptoms of depression.
  • Reduced muscle mass and weakness in the limbs.
  • Blindness.
  • Increased risk for disease.

Orlistat itself has also been shown to potentially cause side effects that include:

  • Blood in the urine.
  • Severe lower back pain.
  • Kidney problems including little to no urination.
  • Liver issues that may cause nausea, itching, loss of appetite, dark urine, fatigue, and yellowing of the skin and eyes.
  • Oily and or fatty stools.
  • Gas and oily discharge.
  • Stomach pain, increased bathroom usage, and rectal pain.
  • Inability to control your bowel movements.
  • Several other side effects

There are also other side effects that if experienced, it’s advised to seek immediate medical help. This can be a sign of serious health problems that can be potentially life threatening if not treated. Compiled in this link are the year’s best weight loss pills.

The official website does list some possible side effects, but a list on Drugs.com features all the possible issues people have experienced.

A clinical study of this ingredient showed very poor weight loss benefits.  The Cochrane Metabolic and Endocrine Disorders Group ran a study showing the effects of the active ingredient when used for over a year:

“compared to placebo, Orlistat reduced weight by 2.9 kg”

2.9 kg is 6.39 pounds. So people lost around 1.87 pounds each month. This is significantly less weight loss than what other supplements can provide. You also have to make sure to consider all the possible side effects, as well as reduce your calories and increase exercise.

The company claims that you can lose around 5% of your total body fat if taken according to their demands, but this still isn’t very much. The added diet and exercise is likely a major part of why there’s weight loss.

FD&C Blue No. 2: Synthetic food coloring added to help provide a blue color. It has no nutritional value, and is only added to make these pills appear blue. Rats given this ingredient were subject to:

“statistically significant increases in brain cancer”

This is according to a study by the Center for Science in the Public Interest.  They also advise that this ingredient should be banned, since it has no nutritional value. It’s also believed that this ingredient may cause hyperactivity as well.

Sodium Lauryl Sulfate: A detergent and foaming agent that may cause skin and eye irritation.

Sodium Starch Glycolate: White powder added to help a pill dissolve and absorb better. It can be extracted from common allergens like wheat and corn. Those allergic or sensitive to these ingredients won’t know which is added, since manufacturers aren’t required to list what extracts are used.

This top 10 list offers a brief outline of the best weight loss pills.

EDITOR’S TIP: Combine this supplement with a proven fat burner such as Sletrokor for better results.

Alli Quality of Ingredients

10 of the 11 ingredients are inactive, meaning they have no weight loss purpose.

The only truly beneficial ingredient is Orlistat, and its results on long term weight loss have been poor. You also have to make sure to take it alongside fats, so people who don’t eat much dietary fats wouldn’t see much improvement.

Clinical studies have shown that it may lead to serious side effects, of which there are many. Other studies have revealed that its weight loss effects are poor. Just over a pound of weight loss is possible each month, which isn’t much. This also comes at the addition of added diet and exercise, as well as special intake considerations, as not all people are advised to take this weight loss pill.

You also have to watch out for fat soluble vitamin loss, which may require extra supplementation with multivitamins.

To get the best weight loss results possible, we advise looking at the top 10 weight loss pills.

The Price and Quality of Alli

Alli is available for purchase in store and in online retail stores. One 40 day supply sells for $69.99 on Amazon.com. So you’re essentially paying $1.74 per pill.

Most of what’s inside this pill has no weight loss effect. It’s mostly made up of food coloring, pill stabilizers, and additives to ease digestion.

The sole active ingredient has been shown to help reduce dietary fats, but its possibility for side effects and vitamin and mineral loss. Also, the weight loss benefits have been incredibly poor, and as you’ll see in the “Customer Opinions of Alli” section, it’s not well reviewed by users.

The year’s best weight loss pills have been carefully ranked in the top 10 list here.

Business of Alli

Alli is owned by the pharmaceutical company GlaxoSmithKline; their US division can be reached below:

Phone Number: (800) 671-2554

Email: [email protected]

No returns are offered on Alli.

The makers have also been the subject of controversy over marketing and illegal actions.  They also were subject to the biggest fine ever imposed on a drug company. The Department of Justice adds:

“Unlawful promotion of certain prescription drugs, its failure to report safety data, and its civil liability for alleged false price reporting”

“largest health care fraud settlement in US history”

They hid information about possible side effects, and they manipulated prices for several of their drugs.

In 2022, they also recalled Alli after fears of contamination.  The FDA adds:

“the company believes some packages of the product were tampered with”

It’s unknown how this could have happened, but they voluntarily recalled all batches of Alli in the US.

For appetite suppression and lasting fat loss we recommend the years best weight loss pills.

EDITOR’S TIP: For the best results, our experts recommend using weight loss pills for at least 3 months. Save your money by buying a few bottles at once.

Customer Opinions of Alli

Several customer reviews are available online. Here’s what a few have experienced:

“hate so much that I paid for a product that did absolutely nothing”

“exercised as I did before, failed to lose any weight”

“It was disgusting and uncontrollable”

“Does not work at all”

Side effects were often listed, and they ranged from loose and oily stools, flatulence, increased bathroom usage, and sudden unexpected stools. A few people mentioned they couldn’t be far away from a bathroom, as they would suddenly get the urge to have to go immedietly.

A lack of weight loss was also listed as a problem. Currently 571 reviews on Amazon.com confirm the lack of beneficial effects. Many struggled to see any weight loss even with proper diet and exercise.

There was often concern that the new batches of Alli just aren’t as good, and that there’s a lack of any noticeable change.

Review the year’s best weight loss pills which were favorited by customers by clicking here.

Conclusion - Does Alli Work?

When considering weight loss pills like Alli, it’s important to look at clinical studies and customer opinions. Many users who tried Alli failed to see any change, and many severe side effects have also been listed. Though Alli can help reduce some fat intake, it only works to reduce fat, and it has no metabolism boosting or other calorie burning effects. So sugar and carbohydrates won’t be reduced.

Also, the possibility for loss of fat soluble vitamins might require extra supplementation. A better solution is available that has only natural ingredients, no laxative like side effects, and great customer reviews. The very best option of 2022 is the all-natural Sletrokor.

It doesn’t require a special diet, and you can rest assured this supplement won’t have laxative like side effects. Customers have also raved about the beneficial and long lasting weight loss effects. You can find these testimonials on their official website, with people leaving nothing but positive weight loss results.

Sletrokor is even backed by a reputable company that produces their formula in a FDA approved facility. Read testimonials, the ingredients list, and see what made Sletrokor our top weight loss pill by clicking here

How Does Alli Compare?
  • Product Name
  • User Rating
  • Has Good Appetite Suppressant
  • Has Only Natural Components
  • Contains No Coffee
  • Alli
  • 31 /100
  • .
  • .

> Leave Feedback

User Feedback

(Page 17 of 20, 389 total comments)


ALI WORKS BUT YOU HAVE TO FOLLOW THE INSTUCTIONS trust me I tried eating a cheesesteak,cheesburger,hot dog and the results were not good and oh yea it does capture 25% of the fat that you intake but if you eat the 3 things that I just told you I ate not only will manure come out of you but so will that 25% of the fat that the Ali captured and its a ton of this Orange sometime yellow Liquid trust me everyone you don't want that each meal that you eat has to be 15g of fat or less if you can do that then you won't have any problems and you won't have these side effects that I'm talking about JUST FOLLOW THE INSTUCTIONS

No happy

I ended up in my doctor's office bad side effects (gas-bloating-oily stools). I couldn't walk without being in so much pain and get into my clothes or wear my wedding ring. This stuff isn't safe to be using. Don't kid yourself. It's not worth it.


yo its great


Alli works for me!!! As promised, I have lost a Ib/week. It will only work if you commit to low fat cal reduced meals!


Orlistat- (marketed under the trade name Xenical by Roche; or over-the-counter as alli[2] by GlaxoSmithKline (pronounced /?ćla?/, like the English word "ally")?also known as tetrahydrolipstatin?is a drug designed to treat obesity. After orlistat was stopped, a significant number of subjects regained weight?up to 35% of the weight they had lost Who wants to be taking pills all their life?

Sacramento Guy

I started Alli a week ago. I follow the plan and have had no "treatment effects." Actually, for the first two days, I didn't poop at all, which concerned me. But on day three, everything was back to normal. The only thing I notice is I'm gassier than normal, especially first thing in the morning. I want to lose 20 pounds, and after just one week, my pants are definitely looser. I don't know if the pill is necessary if you just follow a sensible diet, but I just thought I'd try it for a month and see. I probably won't continue it after this bottle is gone.


I have been on Alli for 2 months and have lost some weight., I am not following a real good diet plan so thats why the results are slow. But I do have to say that even after you stop the pills your stomach doesnt feel right. I was at the mall with my daughter and I had to squeeze my cheeks together to walk around thats why I stopped taking it.


I just Start Alli today i really hope it work cause i have being trying to lose wigth for the the longest im give it time. Im pray about and hope it work.


Well, I just started the pills yesterday...I was extremely nauseous & vomiited at the 2nd dose but.. I plan on sticking it out and giving it a month or so. With all the good reviews & stories I'm confident that this pill will work for me too...I hope ;)


I have been on ALLI for a month now, and have gone down a dress size and 10 lbs since. Trying to lose weight is definitely a hard thing to do. in my 20's, ( everyone knows our metabolism slows down with age) I was successful at going down from a size 12 to a 2 with just diet and exercise, that was it. Now, 2 kids later and in my late 30?s I needed more help. I really think ALLI helped a lot at making this challenge more achievable. I am lucky enough that the treatment effects have been quite tolerable. I know this is a huge factor to consider when deciding to go with or continue the program. I can say I am very pleased with ALLI and will stick to it until I achieve my weight goal. Good luck to everyone!


As a man I feel that Alli is working. The main side effect is frequent soft stools. My wife and I are both using it and are showing small weight loss and have the same side effect.


I have been on Alli for almost a month and have lost close to 12 lbs. I have never lost this fast before. I still eat what i want but only half. I do have the side effects at times. But i am paying attention to what i eat now. And i feel i have changed my eating habits. I know i am losing more than water. or my weight lose would go up and down. I plan on staying on Alli until i lose 50 lbs. what i would like to know is has anyone tried taking more than one per meal? Would you lose more? If the prescrption diet pill was for twice the amount of Alli what would it hurt to increase?


I took Alli for two months in the fall and I didn't lose a single pound. It is not worth it, considering how you feel uncomfortable all day, everyday, and have to use the bathroom every 2 hours.

Expensive Browning

Well, I started taking Alli for about 3 weeks now, My starting weight was 267, I'm currently down to 263. I'm pleased that's 4 pounds in only 3 weeks. I've taken Xenical a generic to alli before and lost 63 pounds within 10 months.With motivation, and a one track mind, anyone can succede their weight lost goal with alli.


well after reading all the comments about alli it seems like having the same results as having your gullbladder out...high fat content you poop alot,so no gullbladder you have to watch what you eat just like alli, i thought about taking it but, i would NEVER leave the bathroom.


im about to start taking Alli and im really nervous because it will be my first time with a diet pill. anything you think i should know?


I did not cheat on this diet, actually, I was usually 2-5 fat grams UNDER what I was supposed to be at and I have had the worst side effects ever. They didn't start until the 2nd week, but man- I am running to the bathroom SEVERAL times a day! I measure my food meticulously so I am positive I am not going over the amount of fat I am supposed to be eating. Also, losing 1 lb in 2 weeks, yeah, not that impressed. I am also an avid exerciser and lost more on Weight Watchers and exercise that on the Alli Plan and exercise. I think I will go back to Weight Watchers and toss this "crappy" pill.

Jody in Odessa

I started taking Alli 6 weeks ago, and I have: 1) lost 21 pounds 2) defecated on the wall of my bathroom 3) ruined 2 pairs of slacks It's great!


I have taken Alli for a couple months now, I love it. With the correct caloric intake...you wont poop your pants! Yes..Ive cheated, and paid! Ruined 4 pairs of pants with a teeeeny tiny fart...Unless your serious, Alli isnt for you. If you are ready for a life change, try it!! It worked and still is working for me.


so, i'm almost twenty & i'm considering taking alli. i'm a bit nervous because of these side effects, but i am willing to do the work. i never lost my baby weight, you could say, in my stomach area. i feel that i'd be much healthier if i lose 20-30 pounds. i weigh about 185 right now, and i'm about 5'4'' - 5'''. does anyone think these are realistic goals for may or june, if it's january now?? also, if i follow the weight watchers plan, you still have to watch for fat intake, right??


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BACKGROUNDBACKGROUND Start the Diet Now Advertisement

Warning: Alli Linked To Liver Damage

The anticipation for a new diet pill is over as the FDA recently approved Alli (pronounced Al-eye). It's the weight loss newcomer that is quickly finding its place on drug store shelves. Alli is the first FDA-approved diet pill available without a prescription. Alli is actually a low-dose version of Xenical, a prescription drug that successfully assists obese individuals losing weight. Xenical is taken under a doctor's care while following a low-calorie, low-fat diet. Alli has the same active ingredient (Orlistat), but in a much lower dosage, and is available without the prescription.

Alli can help you lose a few pounds more than just dieting and exercise alone. It works by suppressing the body's ability to absorb fat in the intestines. By reducing fat, you reduce calories. When the body is unable to absorb these fats they become undigested waste.

Alli works best when it is used in conjunction with a low-calorie, low-fat diet and a regular exercise program. But since sticking to a reduced-calorie diet is tough and since certain foods need to be avoided while using the diet pill, Alli has partnered with eDiets, a meal delivery service that delivers Alli-specific meals to your door every week.

While some may view Alli as a controversial solution to weight loss, the manufacturers of this product have gone to great lengths to offer a comprehensive program to its users in order to make weight loss as easy and approachable as possible.

Although studies on the amount of weight loss you can lose with Alli are limited, you can expect to lose three to five pounds more than just relying on diet and exercise alone.

Do You Know the Best Diet Pills of 2022?

  • May help to jump start a weight loss program
  • Comprehensive website that offers support, food journals, calorie counters, meal plans and shopping lists
  • Partnership with eDiets makes eating and meal planning simple and convenient
  • The only over-the-counter diet pill with FDA approval
  • Low-dose version of effective prescription diet pill
  • Some think it shouldn’t be sold without a prescription
  • Not a long-term solution to weight loss
  • Uncomfortable side effects
  • Must be very careful to not exceed the maximum fat gram requirement with each meal
  • Weight loss affects are modest
  • Meal delivery services don't teach you how to consume and prepare your own calorie and portion-controlled meals

Alli contains 60 mg of Orlistat.


Alli is a 60 mg tablet taken three times a day with meals that should not exceed 15 mg of fat.


A low-fat and low-calorie diet must be followed while taking Alli. Since the success of Alli depends so largely on what you eat, how much you eat and when you eat, you have two choices for designing the most effective meal plan for your weight loss needs:

  • You could consult with your physician or a registered dietitian to design a well-laid out diet and exercise plan.
  • You could sign up for Alli's partner eDiets, a meal delivery service that creates special Alli-approved meals and delivers them to your door each week.

With the eDiets plan, you eat three meals a day plus snack and desserts. Menus can be personalized to reflect your tastes and preferences and you also have access to a registered dietitian, an online community of other Alli dieters and fitness and exercise support.

Since the fat content of each meal must be closely monitored while using Alli (no more than 15 mg each day), eDiets special Alli-approved meals meet these requirements so that your risk of side effects is kept to a minimum.

The eDiets menu includes a wide variety of delicious meals, including:

  • Maple Apple Oatmeal
  • Denver Style Potato Skillet with Turkey Ham
  • Rosemary Pork with Brown Rice
  • Oven Roasted Turkey with Savory Sweet Potatoes and Mixed Garden Vegetables
  • Blackened Chicken served with Seasoned Spicy Brown Rice
  • Peach Cobbler
  • Sugar-free Pudding

Irrespective of which meal plan you follow, since Alli inhibits the absorption of fat-soluble vitamins, it is important to take a daily supplement that includes Vitamins A, D and E.

In addition, for the best results, a regular exercise program should also be followed that includes 30 minutes of exercise on most days of the week. If you decide to sign-up with eDiets meal delivery service, you have access to a live fitness trainer to help you customize an exercise plan to compliment your weight loss needs.


Many people have seen positive results with Alli. However, those considering taking Alli should note that side effects can include gas, and uncontrolled urination and bowel movements, especially when not following the guidelines prescribed by Alli.

Alli is not a magic pill to lose weight, but its special partnership with eDiets, a meal delivery service, makes eating and meal planning simple and convenient.

Do keep in mind that the effects of taking Alli in comparison to just dieting and exercising alone are just the difference of a few pounds. It is necessary that you consult with your medical practitioner before taking Alli.

Common MisspellingsCommon Misspellings

Alle, Ally, Alli Diet, Alli Pill, Alli Diet Pill, Allu, alli.com

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