Metagenics Kaprex Review: Don’t Buy Before You Read This!

Expert rating: stars-icon     By Natalie K (Senior Reviewer) December 11, 2023       Advertising Disclosure

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What is it?

Metagenics Kaprex is a unique daily joint health and pain relief supplement. Their proprietary blend addresses minor joint pain not just by reducing inflammation, as most traditional joint supplements do, but by stimulating a specific kind of immune response in the body with chemicals known as Selective Kinase Response Modulators (SKRMs). Their advertising claims that this approach is safe and effective for both short- and the long-term consumption and that it also has the benefit of increasing cardiovascular, digestive, renal, and hepatic health.

Our panel of nutrition and wellness experts has an ongoing study that rates over the counter joint health supplements, and currently they believe that Flexitrinol is the most effective product on the market for improving joint wellness. Their tests measure flexibility, ease of motion, and reduction of pain levels, and Flexitrinol has scored the highest overall so far. Click her to learn more about Flexitrinol and what makes their products so effective.

Metagenics Kaprex Ingredients and Side Effects
Tetrase Rosemary Oleanolic Acid

 Tetrase: A chemical extract derived from the flowers of the hops plant. Hops are traditionally used to make beer or as a flavoring agent in other food products, however it has also been used medicinally by some cultures.

There is very little clinical data surrounding the medicinal use of tetrase and at this point in time all health effects are mostly speculative, however a recent study did find that it might have some anti-inflammatory properties. In the past it has been used to treat anxiety, insomnia, restlessness, tension, excitability, ADHD, increased urine flow and high cholesterol, but there is insufficient data to say for sure what role in those treatments it actually had.

There is no data about the health effects of long-term tetrase consumption. In the short term there is a possibility that it may worsen depression in some cases, so it is best avoided by any consumers with a history of depression.

Tetrase may also increase or unbalance estrogen production, so individuals with hormone issues and sensitivities should avoid taking supplements with it in them. Tetrase may also worsen certain conditions like breast cancer and endometriosis, and it should be avoided by pregnant or breast-feeding women.

Rosemary: Traditionally a flavoring agent in food products and an additive in potpourris, soaps, and perfumes. There is insufficient evidence that rosemary works for any specific medical conditions, however it has been used by some cultures to treat hair loss, gas, coughs, and toothaches.

Rosemary is safe for most people in moderate doses, however it can become toxic if consumed in larger amounts. Side effects that could potentially be associated with rosemary consumption include:

  • Vomiting
  • Uterine bleeding
  • Kidney irritation
  • Increased sun sensitivity
  • Skin redness
  • Allergic reactions

Oleanolic Acid: A compound found in olive oil that has been shown to have laxative properties and may also help treat high cholesterol and high blood pressure. Some people have attempted to use it in the treatment of some inflammatory conditions, however there is little to no data that supports this application scientifically. Side effects of oleanolic acid consumption include:

  • Repertory difficulty
  • Diarrhea
  • Diabetes complications

There are no studies regarding the long-term effects of daily oleanolic acid consumption. Pregnant or nursing women should not consume oleanolic acid.

Click here to see our panel of wellness experts’ list of the top joint health supplements that are currently available over the counter.

Metagenics Kaprex Quality of Ingredients

Metagenics Kaprex utilizes a highly unorthodox proprietary formula, especially for a joint health supplement. It totally ignores most traditional joint health medications and instead focuses on a brand-new chemical that attacks the problem differently.

Many joint health supplements make anti-inflammatory agents part of their supplement blend because of their ability to reduce the pain and stiffness that is caused by old and damaged connective tissue. The way traditional additives like boron, boswellia, and bromelain work is by blocking the inflammation-causing agent TNF (Tumor Necrosis Factor).

The way Metagenics Kaprex’s lead active ingredient tetrase reduces inflammation is through stimulating a group of enzymes called SKRM’s, which are a part of the body’s immune response.

The science of how effective this approach is overall is still new, though it has some potential to be at least somewhat successful. It remains to be seen if it is more effective or less effective at reducing inflammation than traditional TNF blockers, and there are no studies about the long-term health effects of consuming tetrase on a daily basis.

What Metagenics Kaprex is missing are any ingredients that might actually improve joint health. While tetrase and rosemary could potentially reduce the symptoms of inflammation there is no indication that they might increase collagen production, improve cartilage or synovial fluid health, or do anything to strengthen or repair the ligaments, tendons, bones, and other tissues that make up our connective system.

To learn more about which joint health supplements performed the best in our experts trials measuring increased flexibility and range of motion, click here.

The Price and Quality of Metagenics Kaprex

Metagenics Kaprex is available for purchase through their website for these suggested prices:

  • 1 20-count bottle of Metagenics Kaprex softgels: $21.25
  • 1 60-count bottle of Metagenics Kaprex softgels: $56.25

At first glance that seems to be relatively on par with the average joint health supplement, until you factor in that they are indicated for a two-pill-per-day dosage, which means once shipping and handling are factored in Metagenics Kaprex costs over two dollars a day – nearly double the cost of most average joint health supplements.

Follow this link to see a list of the most powerful joint health supplements available without a prescription.

Business of Metagenics Kaprex

Metagenics Kaprex is manufactured by Metagenics, a health wellness and nutrition sciences company. They list their contact information as:

Phone Number: (800) 692-9400

Address: 25 Enterprise #200

Aliso Viejo, CA 92656

Email: Metagenics does not make an email address publically available, however they do have a customer comment form that can be used to contact them through their website.

It should be noted that Metagenics currently has an “F” rating with the Better Business Bureau based on their history of making misleading or false claims about the medicinal effects of their products. They’ve also been sued a number of times for the same reason, as well as in a case allegedly that they knowingly used toxic fish in the production of their fish oil capsules.

Click here to learn more about which joint health supplements were the safest and most effective for improving overall joint wellness.

Customer Opinions of Metagenics Kaprex

Some of the reviews for Mutagenic Kaprex found online are very positive, however other customers are frustrated with their experiences for a variety of reasons. Here is a sample of some of the criticisms found online:

“I assumed that since it was so expensive it must be good, but I was sorely mistaken – emphasis on the sore.”

“I tried taking Kaprex on the advice of a friend but I immediately developed intense intestinal pain and some other more embarrassing symptoms. I quit taking it and they went away, so I never touched the stuff again.

“This was a total waste of my money – lots of my money.”

The most frequent complaints were regarding the price and the effectiveness of Metagenics Kaprex, however there were also some complaints of side effects, mostly gastro-intestinal in nature.

Follow this link to see our team of experts’ complete list of the best joint health supplements on the market.

How Does Metagenics Kaprex Compare?
  • Product Name
  • User Rating
  • Good Company Reputation
  • Quality Ingredients
  • Money Back Guarantee
  • Metagenics Kaprex
  • 31/100
Conclusion – Does Metagenics Kaprex Work?

Given the highly experimental nature of the ingredients of Metagenics Kaprex and the mixed nature of the customer reviews found online, it is difficult to say if any given user will experience benefits or not. If they do, it seems most likely that the benefits will be of an anti-inflammatory nature with possible reductions to joint pain and stiffness.

Their products are indicated on the bottle and in their advertising for joint health specifically, however that is a somewhat confusing designation given that there is nothing in Metagenics Kaprex that works to improve collagen production, cartilage health, or joint repair and functionality specifically.

Traditional joint health supplements will use ingredients like glucosamine, chondroitin, and MSM that actually help stimulate the biological processes that lubricate, cushion, and reinforce joint tissues so that they do not become irritated and inflamed to begin with.

It may be most effective to pair Metagenics Kaprex with a basic glucosamine and chondroitin supplement that also contained some more traditional TNF-blocking anti-inflammatories. Given the already exceptionally high price tag on Metagenics Kaprex, however, many consumers would find that option to be somewhat cost prohibitive.

Lastly, given the untested nature of Metagenics Kaprex’s ingredients, especially when it comes to long-term health effects, users are warned that they take these supplements at their own risk and the potential for conditions to arise after prolonged usage is always a possibility.

Our experts currently have Flexitrinol ranked as their most effective joint health supplement available without a prescription. Flexitrinol performed the best in their trials measuring flexibility, range of motion, and pain reduction, and has proven to be safe for nearly all users. Click here to learn more about what goes into Flexitrinol that makes it so effective.

2 Responses to Metagenics Kaprex Review

Sally says:

Kaprex works! I’ve used it for over 10 years and suffered no ill effects whatsoever. When I use i, I’m pain free. If I don’t, I have achy knees. I’m a believer in Kaprex!

Ann says:

Kaprex and Omega 3 were given to me by a top notch doctor at Scripps many years ago when RA had hit me so hard I was close to being crippled. After a couple years of taking only those two items and no prescription drugs for RA, I have no pain, no deformities (which another doctor warned I would have if I didn’t take the prescription meds he prescribed) and after two years I live my life as if I don’t even have RA. Each person is different, but I was saved from life in a wheelchair like my brother with RA and who was on prescription meds and suffered many side effects til his death.

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