Perricone MD Cold Plasma Review: Don’t Buy Before You Read This!

Expert rating: stars-icon     By Natalie K (Senior Reviewer) November 27, 2020       Advertising Disclosure

User Rating:


stars-icon + -
What is it?

Perricone MD Cold Plasma is an anti-aging face treatment designed for use as a comprehensive and non-invasive solution to the effects of aging, and said to be suitable for all skin types.  The product is supposed to deliver results   Dr. Nicholas Perricone, the developer of the Cold Plasma line, claims the powerful ingredients and advanced technology of his cosmeceuticals will:

  • Dramatically fight lines and wrinkles
  • Firm skin and restore elasticity
  • Balance uneven skin tone and reduce discoloration
  • Soothe complexion
  • Purify pores
  • Smooth skin imperfections

The unique patented Cold Plasma formula employs a process by which insulated ions carry nutrients to the places they are most needed in the skin, allowing for personalized results.

Our review experts have researched and tested many different anti-aging treatments, and have named Kremotex as the best option.  All-natural and made with apple stem cells, shea butter, and other natural ingredients at the forefront of anti-aging science, users are praising its immediate and dramatic results.

Click here to see before and after pictures, and find out what benefits Kremotex can offer you.

Perricone MD Cold Plasma Ingredients and Side Effects

Active ingredients in Cold Plasma believed to provide anti-aging benefits:

Palmitoyl Tetrapeptide 3 Dimethyl MEA (DMAE) Acetyl Hexapeptide 8 Tocotrienols
Palm Oil Dimethicone Butylene Glycol Glycerin
  • Palmitoyl Tetrapeptide 3: Synthetic peptide that suppresses production of interleukins, the chemical messengers responsible for triggering inflammatory response.
  • Dimethyl MEA (DMAE): An amine believed to contain anti-aging and anti-inflammatory properties, and also used to adjust the pH balance in some products.
  • Acetyl Hexapeptide 8: Synthetic peptide compound used to reduce the facial contractions that lead to fine lines and wrinkles.
  • Tocotrienols: Powerful Vitamin E compound thought to promote regeneration and healing.
  • Glycerin: Naturally derived from plant and vegetable oils, glycerin is commonly used in skin care products to moisturize skin, and soothe irritation.
  • Palm Oil: Vegetable oil derived from the fruit pulp of oil palms, contains Vitamin E, a powerful antioxidant that prevents aging.
  • Dimethicone: Silicone based, organic polymer that forms a barrier on the skin, sealing in moisture. It is also easily spreadable, and leaves skin silky and smooth to the touch.
  • Butylene Glycol: Chemical compound derived from petroleum, used in skin care products as a solvent, thinner, and conditioning agent.

Perricone MD Cold Plasma Quality of Ingredients

Perricone MD Cold Plasma makes no secret of its ingredients, which is good for those who take an active interest in the products they apply to their skin.  Cold Plasma’s proprietary formula is a combination of natural and synthetic ingredients, all linked to anti-aging science.  As an alternative to painful and expensive cosmetic surgical procedures, Cold Plasma may be the ideal product for consumers concerned about the effects of aging.

There are, however, concerns about some of the ingredients.  These should be considered before committing to purchase, as Cold Plasma has a very high price point.  Despite claims that it is ideal for all skin types, not all skin types react the same way to certain ingredients:

“Within hours of applying the Product I felt very itchy in fact it woke me up. By the next afternoon I had tiny red blisters scattered all over my neck.”

Additionally, some ingredients may not perform as well as the product claims. The ingredient Dimethyl MAE (DMAE), for example, has shown conflicting results.  Its initial inflammatory benefits encourage users to keep using it, but some research suggests that prolonged use may have reverse effects.  Over time, DMAE can actually start to destroy the skin cells that promote healthy collagen production.

Before using Cold Plasma, or any skin care product, one should always check with a doctor to discuss the possible risks associated with the ingredients.

Visit link to see which all-natural, age-defying skin cream tops the 10-best list.

The Price and Quality of Perricone MD Cold Plasma

One 1-ounce jar of Cold Plasma costs $162 with free shipping (paid options available for faster delivery).  Like many other skin care products, a “replenishment service” is offered, in which you are billed automatically for future shipments.  Unlike some companies, however, you must select this option when you place the order, rather than missing the terms in fine print, and inadvertently subscribing to the service.

Still, some customers have had negative experiences with the replenishment service, and then again with customer service when trying to correct their issues:

“I don’t think they want to improve the refund/return process. They just want to keep sending product and billing customers.”

Another customer gave Perricone MD many opportunities to satisfy their skin care needs, but simply did not feel any product offered was worth the cost:

“I once ordered every product Perricone. None worked half as good as my $26.00 moisturizer”

There were mixed customer opinions regarding the value.  Many thought it worked fine, but did not see any dramatic changes:

“I didn’t see any difference in my skin. It’s not the miracle product they claim.”

Check out which products made the list of top-rated anti-aging skin creams for the best value.

Business of Perricone MD Cold Plasma

The manufacturer of Cold Plasma is NV Perricone LLC.  Their contact info is:

Phone: 1-888-823-7837

Address: NV Perricone LLC

600 Montgomery Street

Suite 2500

San Francisco, CA 94111

Email: [email protected]

There are over 70 documented complaints against NV Perricone LLC through the Better Business Bureau. Some complaints have been closed to the satisfaction of the consumer, but only after filing the complaint.  Many responses on behalf of NV Perricone LLC apologized for the “miscommunication,” and issued immediate refunds, which is usually all the consumer had asked to begin with before finding it necessary to involve the BBB.

“They misrepresented themselves and charged my card WITHOUT MY AUTHORIZATION.”

“I have canceled this product several times. After calling 4 times and speaking to rude customer service representatives, they tell me the only way to stop the delinquent bills is to pay up.”

Click here for a comprehensive list of the best age-defying creams compiled by review experts.

EDITOR’S TIP: For the best results, our experts recommend using anti-aging creams for at least 3 months. Save your money by buying a few bottles at once.

Customer Opinions of Perricone MD Cold Plasma

The customer reviews of Cold Plasma range from nothing but positive to not at all satisfied.  Many negative customer opinions are as a result of a complicated returns process and poor customer service, but most negative opinions state that the product simply does not do what it promises, and it is not worth the hefty price tag.

Not all skin care products perform the same for all skin types, so  luckily there are many online reviews available, in order to make an informed decision.

Perricone MD Cold Plasma can do no wrong in some customers’ eyes:

“Perricone cold plasma Md products are the best ever. Have been using them for a year now and amazing differences… I love this stuff and hope they never stop making it.”

Another glowing review from a customer who believes Cold Plasma is worth every penny:

“I don’t know if these products or this specific regimen will work for everyone, and I know they are really expensive, but this has worked for me when nothing else has.”

But for every positive review, it seems there was a negative counter.  A common issue for many was the smell, which was bad enough to turn many users off:

“I used this Perricone cream. The odor made me nauseous. I decided to use on my neck. Did not work at all. I will not ever buy this cream again. I do not recommend.”

“I attempted to use this product three times and couldn’t help gagging. My face smelled like a dead mackerel.”

It is no wonder the reviews for Cold Plasma are mixed, since the efficacy of any skin care product depends on individual skin type, allergies, whether or not product is used as directed, and many other contributing factors.

To find out which anti-aging cream our review experts have named the best, click here.

How Does Perricone MD Cold Plasma Compare?
  • Product Name
  • User Rating
  • Good Company Reputation
  • Quality Ingredients
  • Money Back Guarantee
  • Perricone MD Cold Plasma
  • 36/100
Conclusion – Does Perricone MD Cold Plasma Work?

Perricone MD Cold Plasma makes many claims:

  • Comprehensive product addresses all 10 signs of aging.
  • Science-backed research.
  • Precise technology for personal results.

Cold Plasma without a doubt works wonders for many pleased customers, but the negative and neutral reviews cannot be ignored.  These concerns are not the same for every user, but they are fairly common complaints:

  • Nauseating smell
  • Severe rash
  • Uncontrollable itching
  • No results at all, after months of use
  • No sunscreen
  • Claims of 5-years of research, none available to public
  • Very expensive
  • Customer service and billing issues as a result of “miscommunication”

All of these concerns should be taken into account when deciding which anti-aging cream is right for you.

And until the alleged results of “5 years of research” is published, or at least made available in summarized form to the public, the jury is still out on Perricone MD Cold Plasma.

Our expert reviewers researched and compared many age-defying products and agree: Kremotex is the best overall. Its fast-acting ingredients boost collagen production, and essential antioxidants and vitamins promote cell regeneration, reversing the effects of aging and skin damage.

Many positive testimonials on their website, along with amazing before and after transformation photos show why Kremotex was voted the best anti-aging cream of 2021. Learn more about the science of Kremotex, and see before and after results by visiting this link.

3 Responses to Perricone MD Cold Plasma Review


I bought the Perricone system. Total rip off. Plus they keep sending it to you and billing your credit card every month, no matter what you do! Finally, cancelled my credit card and they still sent me the product and billed me!!!! Now I have to worry about my credit score since this will probably go to collections. DO BE FOOLED AND RIPPED OFF LIKE I WAS!!!!!!!!!!

PAB says:

the beauty consultant at Ulta Beauty Store recommend that I try this product on 2/10/18. I asked her if it was hypo-allegenic because I have sensitive skin. She assured me that it was. Within seconds of it being applied to my face, I began to feel a burning sensation. When I looked in the mirror, my face was beginning to swell and turn red! She was shocked by the reaction and used witch hazel. to try and counteract the reaction. It helped bu the swelling continued. The manager of the store tried to contact the company, no response. I left the store and headed to the nearest Urgent Care. I stopped along the way and washed my face with soap and water from a convenience store. The burning eased and within a couple of hours, the swelling went away. I would be very skeptical about the ingredients in this product and not use it if you have sensitive skin.

IS says:

I got a severe rash on my neck and itches. it’s been over a month and it’s still there. Have to see my doctor, this is very disturbing.

Leave a Reply to JULIE FREEMAN Cancel reply

Your email address will not be published.