Progest E Review (UPDATED 2024): Don’t Buy Before You Read This!

Expert rating: stars-icon     By Natalie K (Senior Reviewer) May 9, 2024       Advertising Disclosure

User Rating:


stars-icon + -
What is it?

Progest E is a progesterone oil meant to be taken orally in an effort to balance levels of the hormone inside the body. Progest E also has the secondary use as a topical solution for acne, wrinkles, sun damage and other skin conditions.

Progest E gets its natural hormone blend from soy and wild yam. The makers of this product claim this product is entirely bioidentical and will stimulate your body to naturally produce progesterone on its own.

In looking at a wide range of products designed to tackle menopause and its myriad symptoms, Femmetrinol is the one we keep recommending. Made with herbal ingredients like black cohash, wild yam and chasteberry, this product eases hot flashes and night sweats and provides a sense of emotional balance with daily use. Click here to learn how Femmetrinol can help you deal menopause with no trouble at all.

Progest E Ingredients and Side Effects

Progest E is a unique supplement in that it’s a liquid product intended for oral consumption and it must be kept in the refrigerator. While multiple sites list the ingredients used to make this product, there’s no official label that was posted for consumer evaluation. Based on what we’ve learned about Progest E, here is what you can expect to find inside:

Soy Isoflavones Wild Yam

Soy Isoflavones: Soy contains chemicals known as isoflavones (called genistein and daidzein), which are thought to mimic the effect of certain hormones inside the body.

Isoflavones are often used to help regulate hormone balance, resulting in relief from menopausal symptoms like hot flashes, mood swings or night sweats.

Something worth mentioning—this ingredient has been associated with both exacerbating hormone-sensitive breast, ovarian or endometrial cancers, as well as reducing the risk.

Users may want to talk to a doctor before taking a product containing soy if they have one of these cancers or are at a higher risk of developing these conditions.

  • Side effects may include gas, bloating or an allergic reaction with use.

Wild Yam: A plant that contains a compound known as diosgenin, which may be made into various steroid hormones like DHEA or estrogen. Wild yam is thought to help women reduce hot flashes during menopause and is marketed as a natural alternative to hormone replacement therapy.

Click here for a deep dive into the supplements that best treat menopause symptoms.

Progest E Quality of Ingredients

The information we found discussing the formula used to make Progest E was not entirely clear as far as the full breadth of contents were concerned. We were unable to locate an official label, but this product is featured on a number of sites that mentioned that this product contains wild yam and soy-based hormones.

There could be other ingredients in the mix, but we don’t have access to that information. Based on what we know, wild yam and soy both do have an effect on the body’s natural production of hormones—which could make this an effective solution for women going through menopause, as well as others who are having problems with menstruation, fertility or other issues.

Progest E could be effective, but this product isn’t available across very many channels, and aside from a few forum entries here and there, there aren’t a whole lot of people who have elected to recount their experience using this product.

Learn more about how you can finally achieve hormonal balance – more after the jump.

The Price and Quality of Progest E

Progest E may be purchased on a few different websites, such as and This product ranges in price from about $30-$40 for a small bottle containing 1.15 ounces.

Unfortunately, this product does not seem to be featured on any official webpage and is not for sale by any more reputable retailers like Amazon, GNC, Walmart, and so forth.

While we don’t have too much information about this product, the price point does seem a bit high, considering there are a number of soy isoflavone supplements, natural progesterone creams or pills that all cost considerably less than this particular product.

Click here to read about treating night sweats and hot flashes with plant-based estrogens rather that HRT.

Business of Progest E

Progest E was developed by a naturopath named Dr. Ray Peat, who operates a website and forum dedicated to a confusing blend of hormone science, art and more. Dr. Peat doesn’t actually sell this product on his site, but has partnered with some of the lesser known e-commerce channels outlined above.

While Dr. Peat offers an interesting web presence, there’s nothing that comes up regarding any deceptive supplement sales or other exploitative practices you’ll sometimes find when doctors develop natural supplement lines.

There’s a lot of talk, especially on the Long Health website about how to take this product (3 drops a day, orally), as well as the many issues it aims to address (PMS, hot flashes, night sweats, fibrocystic breasts, etc.), but we don’t have much insight into the science behind this product, nor do we know the full extent of the ingredient.

On perhaps a less important note, the label of this product looks very much like someone made this at home with a printer and measured out the ingredients without the proper materials on hand. You can’t always judge a product based on appearances, but the lack of a website, combined with the look of the product makes us a bit wary of its safety and efficacy.

Customer Opinions of Progest E

Progest E is made by a company with very little brand recognition, which shouldn’t speak too much to the quality, though it makes it a bit difficult to find a large pool of reviewers to base a recommendation on. Regardless, we were able to locate a few accounts of those who had used this product. Here’s a look at what they had to say:

“I took this product as directed, 3 drops twice a day and after using for a few days, found I was feeling tired and almost drugged. I’m starting to feel better, but don’t know if this is supposed to happen or not.”

“I was not very well informed when I started taking this product. I had an undiagnosed thyroid condition and it wasn’t working. Definitely talk to a doctor before blindly taking a new supplement.”

 “The progesterone made me feel nice and relaxed, when before, I felt irritable and moody. Unfortunately. It does make me feel slightly hungover after using.”

The comments posted by users were not especially informative, and in looking at the Dr. Peat forum (where we found these reviews) it seems Progest E is part of a diet recommended to all kinds of people, regardless of whether or not they need to be taking a progesterone supplement.

Unfortunately, while this product is likely designed for menopause symptoms that come from low progesterone, there weren’t any accounts documented from people in this group.

Based on the lack of information we have about the use of Progest E in treating the range of menopausal symptoms, we recommend users look for a product with more documented use for this indication, otherwise it may not be worth the investment.

Get more information about how herbal supplements can ease your menopause symptoms — click here.

Conclusion – Does Progest E Work?

Overall, Progest E could be very much in line with its larger competitors. Should the ingredient profile reflect the somewhat vague information listed on the websites where it is sold, users can expect some changes in hormone levels, and perhaps some relief from menopausal symptoms.

On the other hand, some of the reviews we came across reflected a negative users experience, with people reporting that they felt dizzy, tired or slightly “off” after using this product only a few times.

We also don’t have enough information about this product as a whole—there are very few reviews, most of which are documented on Dr. Peat’s forum for “discussing his ideas,” nor are there any cited clinical studies, or even a picture of the label for review.

There’s also no website, and the only channels this product is sold on are smaller online retailers that look a bit outdated and provide zero credibility for an already little-known product.

Based on the information we’ve gathered, we have come to the conclusion that there are many other solutions out there that provide similar benefits for less money, or that simply can do it better.

After evaluating a variety of products, we’ve found that Femmetrinol is the menopause supplement out there. This product uses a blend of safe and proven ingredients to bring relief to women from the long list of menopause symptoms from irritability to anxiety, hot flashes, night sweats and more.

Femmetrinol is made in an FDA-certified facility and has been subject to a number of quality control procedures to ensure consumers get an effective solution with every purchase. Click here to learn more about the herbal formula behind Femmetrinol.

7 Responses to Progest E Review

Laura says:

I read about this product from a book by Elaine Hollingsworth Take Control of your Health I bought 6 bottles I have been taking it for a few months but aam still getting hot flushes ……not sure really how much to take

Lj says:

I’ve been taking progest-e for many years. I have PCOS, endometriosis and fibroids. I take WAY more than the normal 3 drops due to my conditions. I sometimes take 30 or so in the morning (and again at night if needed). Many people may need much less but due to my PCOS I need much higher doses. It’s also calming which amazes me. I increased my doses until my symptoms went away which helped me find the correct dose for me. I notice a huge difference when I forget to use it for a few days or weeks when I get busy. Keep it in the refrigerator as well. Lasts a long time. Can’t imagine my life without this.

Anonymous says:

Great product ☆☆☆☆☆

Anonymous says:

I’ve been using progest E complex by Kenogen for about 6 months no side effects defiantly no drowsiness at 5am each morning I use 3 drops and place on my gum to dissolve.I don’t suffer from night/day sweats and I feel I’m not on an emotional roller-coaster any more. Long natural health…

Lj says:

I absolutely love Progest-e. It’s changed my life.

Kitty Corbett says:

My holistic doctor prescribed Progest-E for me, of which I was to take six drops at bedtime. He didn’t say what condition he was addressing, and now in my 80’s I am long past menopause. Nevertheless, while I was taking it I found I had fewer bathroom trips during the night, even none at all. He no longer stocks Progest-E, I haven’t had any for months now and find I must get up once or twice every night for a bathroom trip. But it is expensive.

Maya says:

What is the best way to take it for old women: before meals(how long?), after meals (how long?), during meals?

Leave a Reply

Your email address will not be published. Required fields are marked *